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Archive the most commonly used second-line therapies include high-dose amoxicillin clavulznate, second-generation cephalosporins (eg, cefuroxime, cefpodoxime), macrolides (eg, azithromycin, clarithromycin), fluoroquinolones (eg, ciprofloxacin, levofloxacin), and clindamycin.
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