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| Plasmid-mediated resistance to third-generation cephalosporins caused by point mutations in tem-type penicillinase genes. | Simplicrf is a once-a-day cephalosporin antibiotic used to treat skin infections (wounds and abscesses) caused by susceptible strains of bacteria. | Effective for complicated skin and soft tissue infections caused by staphylococci, streptococci, and enterococci. The cefpodoxime mic was or the mic of an extended-spectrum cephalosporin was for 81 of the 264 isolates. |
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